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BIPARTITE AND TRIPARTITE SIGNALING IMMUNE CELLS
BIPARTITE AND TRIPARTITE SIGNALING IMMUNE CELLS
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机译:BIPARTITE和TRIPARTITE信号免疫细胞
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摘要
Embodiments of the disclosure include compositions and methods effective for immunotherapy, such as for cancer. The embodiments include cells that recognize a combination of two signals or three signals present at the tumor microenvironment. In certain embodiments, the signals for antigen stimulation, co-stimulation, and cytokine signaling act through separate molecules, although in certain embodiments the signals for antigen stimulation and co-stimulation are transmitted through the same molecule.
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