RADIOLABELED TRACERS FOR POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1), METHODS AND USES THEREFOR

摘要

To provide pharmaceutical compositions for treating poly (ADP-ribose) polymerase-1 (PARP-1)-related diseases.SOLUTION: The present invention provides the following compound [where, R is a fluoroethyl group]. The PARP-1-related disease is selected from cancer or inflammation. The PARP-1-related disease is abnormal inflammation of lung. The subject is a human, a cat, a dog, a mouse, a guinea pig, a rabbit, a rat, a horse, a sheep, a cow, or a goat.SELECTED DRAWING: None