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Pharmacokinetic analysis method, pharmacokinetic analysis device and program

机译:药代动力学分析方法,药代动力学分析装置和程序

摘要

We propose a pharmacokinetic analysis method and the like that can easily analyze changes in the pharmacokinetics of the patient in response to changes in the patient's physiological function. Using the input physiological function of the patient, the individual pharmacokinetic calculation unit 21 calculates the individual pharmacokinetic value of the patient using a mathematical model, and the group pharmacokinetic acquisition unit 25 calculates the group pharmacokinetic value of the group to which the patient belongs. Get The coefficient of variation calculation unit 29 calculates the coefficient of variation from the personal pharmacokinetic value and the population pharmacokinetic value. The population change pharmacokinetic acquisition unit 41 obtains a change in the average pharmacokinetic value of the population in response to the input change in physiological function. The patient change pharmacokinetic system dark part 45 takes advantage of the fact that the variation coefficient is constant even if the physiological function changes, and uses the change in the average pharmacokinetic value of the population and the change in the individual pharmacokinetic value of the patient using the change coefficient. Get
机译:我们提出了一种药代动力学分析方法等,其可以容易地分析患者的药代动力学响应于患者的生理功能的变化而变化。使用患者的输入生理功能,个体药代动力学计算单元21使用数学模型来计算患者的个体药代动力学值,并且组药代动力学获取单元25计算患者所属组的组药代动力学值。 Get变异系数计算单元29根据个人药代动力学值和总体药代动力学值来计算变异系数。群体变化药代动力学获取单元41响应于所输入的生理功能变化来获得群体的平均药代动力学值的变化。患者改变药物代谢动力学系统暗部45利用以下事实:即使生理功能改变,变化系数也是恒定的,并且使用人群的平均药物代谢动力学值的改变和患者的个体药物代谢动力学值的改变。变化系数。得到

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