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Modified cyclodextrins for the selective sequestration of fentanyl related compounds and uses thereof
Modified cyclodextrins for the selective sequestration of fentanyl related compounds and uses thereof
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机译:用于选择性螯合芬太尼相关化合物的改性环糊精及其用途
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摘要
Novel thioalkylcarboxylate-modified CDs and pharmaceutical compositions comprising these thioalkylcarboxylate-modified CDs are disclosed, as well as methods of using the disclosed thioalkylcarboxylate-modified CDs and pharmaceutical compositions thereof to neutralize or reduce undesired effects or symptoms associated with one or more fentanyl related compounds in a subject in need thereof. The use of the disclosed thioalkylcarboxylate-modified CDs to detect the presence of one or more fentanyl related compounds in a sample is also disclosed, which comprises contacting the sample with said thioalkylcarboxylate-modified CDs or a composition comprising these CDs.
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