Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff

摘要

Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve using a cuff to apply pressure to an artery in a subject to determine a plurality of baseline values for a parameter related to endothelial function as a function of applied pressure (P_m); b) applying a stimulus to the subject; and applying external pressure P_m to the artery to determine a plurality of stimulus-effected values for the parameter related to endothelial function as a function of applied pressure (P_m); where the baseline values are determined from measurements made when said mammal is not substantially effected by said stimulus and differences in said baseline values and said stimulus-effected values provide a measure of endothelial function in said mammal.