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Alkyl quinolones as biomarkers of pseudomonas aeruginosa infection and uses thereof

机译：烷基喹诺酮类药物作为铜绿假单胞菌感染的生物标志物及其用途

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摘要

A method of determining the P. aeruginosa or related species infection status of a subject comprising: (i) providing a sample of material obtained from the subject; (ii) determining the level of one or more alkyl quinolones or metabolites thereof produced by P. aeruginosa or a related species in the sample

机译：确定 P的方法。受试者的铜绿假单胞菌或相关物种感染状况，包括：（i）提供从该受试者获得的材料样品; （ii）确定由I P产生的一种或多种烷基喹诺酮或其代谢物的水平。样品中的铜绿或相关物种 展开▼

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公开/公告号US10139406B2

专利类型

公开/公告日2018-11-27

原文格式PDF

申请/专利权人 THE UNIVERSITY OF NOTTINGHAM;
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申请/专利号US201414891242

发明设计人 MIGUEL CAMARA;ALAN SMYTH;DOUG FORRESTER;NIGEL HALLIDAY;ALAN KNOX;DAVID BARRETT;ANDREW FOGARTY;HELEN BARR;PAUL WILLIAMS;
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申请日2014-05-13

分类号G01N33/569;C07D215/22;C07D215/24;C07D215/26;C07H17/02;C07K16/12;C12Q1/04;G01N33/84;

国家 US

入库时间 2022-08-21 12:09:20

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4. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa [J] . Geoffrey D. Vrla, Mark Esposito, Chen Zhang, PLoS Pathogens . 2020,第9期

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