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LOW-FREQUENCY MUTATIONS ENRICHMENT SEQUENCING METHOD FOR FREE TARGET DNA IN PLASMA
LOW-FREQUENCY MUTATIONS ENRICHMENT SEQUENCING METHOD FOR FREE TARGET DNA IN PLASMA
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机译:血浆中游离目标DNA的低频突变富集测序方法
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摘要
The present invention provides a low-frequency mutation enrichment sequencing method for free target DNA in plasma, comprising plasma DNA extraction and library construction, general library TT COLD PCR amplification enrichment, probe enrichment capture, PCR and sequencing of captured products, and positive and negatice double-strand error-correction low-frequency information analysis.
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