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Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
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机译:褪黑素与镇静和/或止痛成分合用的控释组合物
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摘要
Controlled-release therapeutic compositions including melatonin combined with sedative and/or analgesic ingredients are described. The compositions have a solid core including melatonin in an acidified polymeric matrix. A sedative ingredient such as GABA receptor agonist may also be in the acidified polymeric matrix. The composition may include an expedited release portion providing a burst release of active ingredients and a sustained release portion providing a sustained release of active ingredients.
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