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MASS SPECTROMETER AND BIOLOGICAL SAMPLE ANALYSIS METHOD USING SAID MASS SPECTROMETER

机译:所述质谱仪的质谱仪和生物样品分析方法

摘要

In a PESI ion source, a solvent supply unit (8) is placed above the liver (101), which is the object of measurement, and by moving a probe (6) up and down such that the tip of the probe (6) passes through the solvent supply unit (8) and is inserted into the liver (101), a sample is captured by the tip of said probe. The solvent supply unit (8) includes a container unit comprising a liquid-blocking upper film body (81) stretched over the bottom surface opening of a cylindrical body (80), and a liquid-blocking lower film body (82) which is stretched out approximately in parallel with the upper film body (81) with a spacer interposed therebetween; the container unit houses a solvent (84). Because the tip of the probe (6) passes through the solvent (84) during the up-and-down movement of the probe (6), sufficient solvent adheres to the sample and when a high voltage is applied to the probe (6), components in the sample are favorably ionized. Blood seeping from the liver (101) upwards through the hole through which the probe (6) was passed spreads in the periphery of the lower film body (82) and is not admixed into the solvent (84) in the container unit. By this means, it is possible to avoid blood from acting as a contaminant during measurement.
机译:在PESI离子源中,将溶剂供应单元( 8 )放在要测量的肝脏( 101 )上方,并移动探针(< B> 6 )上下移动,以使探针( 6 )的尖端穿过溶剂供应单元( 8 )并插入肝脏( 101 ),样品被所述探针的尖端捕获。溶剂供应单元( 8 )包括容器单元,该容器单元包括在圆柱体()的底表面开口上拉伸的阻液上膜体( 81 )。 80 )和阻液性下膜体( 82 ),其与上膜体( 81 )大致平行地延伸,并带有垫片介于两者之间;容器单元中装有溶剂( 84 )。因为探针( 6 )的上下移动过程中探针的尖端( 6 )通过溶剂( 84 ) ),足够的溶剂附着在样品上,并且在探针( 6 )上施加高电压时,样品中的成分会被离子化。从肝脏( 101 )向上穿过探头( 6 )穿过的孔向上渗出的血液在下膜体( 82 < / B>),并且不会混入容器单元中的溶剂( 84 )中。通过这种方式,可以避免在测量期间血液充当污染物。

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