Embodiments of a method are disclosed for using molecular arrays (peptide arrays) to define networks of functionally linked molecules. This is accomplished via competition experiments in which molecules from the array are added to solution, specifically inhibiting the function (e.g. binding of an antibody) of the similar molecule in the array as well as any other molecules in the array that would have the same function. These networks of functionally linked molecules are very useful in both understanding the chemical nature of the function and in improving the statistical robustness of functional detection on the array, e.g. defining a robust immunosignature in an immunosignature application.
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