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SiRNA and their use in methods and compositions for inhibiting the expression of the ORAI1 gene
SiRNA and their use in methods and compositions for inhibiting the expression of the ORAI1 gene
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机译:SiRNA及其在抑制ORAI1基因表达的方法和组合物中的用途
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摘要
The invention relates to si RNA molecules and their use in methods and pharmaceutical compositions for inhibiting the expression of the ORAI1 gene. The invention also relates to the use of said si RNAs molecules in the treatment and/or prevention of an eye condition characterized by increased expression and/or activity of ORAI1 gene, preferably said eye condition is conjunctivitis and/or an ocular allergy such as seasonal allergic conjunctivitis, perennial allergic conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, and giant papillary conjunctivitis.
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