compound, pharmaceutical composition, and methods for improving bone metabolism, for preventing or treating a disease associated with bone metabolism, and for preventing or treating osteoporosis.

摘要

compound, pharmaceutical composition, and methods for improving bone metabolism, for preventing or treating a disease associated with bone metabolism, and for preventing or treating osteoporosis. A new low molecular weight compound having ossification promoting activity is provided. the new low molecular weight compound is a compound represented by the general formula (i) (i) (where r ^ 1 ^ and r ^ 2 ^ are hydrogen atoms, and the like; r ^ 3 ^ is a hydrogen atom, and the x, y and z are nitrogen atoms, and the like; a is a feline group and the like; n is 1 or 2 and the like; vew are oxygen atoms and the like) or a pharmaceutically acceptable salt thereof .