SYNTHETIC PEPTIDE THAT IS IMMUNOLOGICALLY REACTIVE WITH AN ANTI-CITRULINTED PROTEIN ANTIBODY, ITS USE AND ITS METHOD OF IDENTIFICATION, AS A KIT UNDERSTANDING SUCH PEPTIDE

摘要

Synthetic peptide that is immunologically reactive with an anticitrulinated protein antibody, its use and method of identification, as well as a kit comprising said peptide The present invention provides novel citrullinated peptides for use in methods to help, assist, enhance, or facilitate the diagnosis or prognosis of rheumatic diseases such as rheumatoid arthritis (ra), and methods for identifying novel citrullinated peptides that are immunoreactive with anti-citrullinated protein antibodies (acpas). The present invention also provides methods for detecting rheumatoid factor (RF) using novel RF detection reagents as a means to assist, assist, improve, or facilitate the diagnosis or prognosis of rheumatic diseases such as RA. Kits comprising at least one of the novel citrullinated peptides and / or RF detection reagents of the present invention are also provided.