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Method of increasing production of polyunsaturated fatty acids Omega -3 in microalgae

机译:增加微藻中多不饱和脂肪酸Omega -3产量的方法

摘要

This revelation presents, in one respect, a method for producing enriched lipids for EPA, comprising modifying a microalga e to increase the expression of pfa1 and /or pfa3, and cultivating the modified microalga e under conditions allowing the expression of pfa1 and /or pfa3, under which I have read them Enriched penises for EPA are produced. A recombinant microalga e is also shown in which pfa1 and /or pfa3 is overexploited. It has been shown in this document that such recombinant microalgae produce very favourable fatty acid lipid profiles (e.G. Increased EPA levels, increased EPA ratio:dha, decreased levels of DPA n -6, etc.).
机译:在一个方面,该启示提出了一种生产用于EPA的富集脂质的方法,该方法包括修饰微藻以增加pfa1和/或pfa3的表达,并在允许表达pfa1和/或pfa3的条件下培养修饰的微藻。 ,据我所读,它们产生了EPA的丰富的阴茎。还显示了重组微藻,其中pfa1和/或pfa3被过度利用。在该文献中已经表明,这种重组微藻产生非常有利的脂肪酸脂质谱(例如,增加的EPA水平,增加的EPA比率:dha,降低的DPA n -6水平等)。

著录项

  • 公开/公告号BR112018073164A2

    专利类型

  • 公开/公告日2019-04-30

    原文格式PDF

  • 申请/专利权人 DSM IP ASSETS B.V.;

    申请/专利号BR20181173164

  • 发明设计人 ANNE-CECILE V. BAYNE;ROSS E. ZIRKLE;

    申请日2017-05-11

  • 分类号C12N1/12;C12N9/10;C12N15/82;C12P7/64;

  • 国家 BR

  • 入库时间 2022-08-21 12:03:24

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