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Chiral pyrrolidinium salt with a fragment of natural terpene and method for producing chiral pyrrolidinium salt with a fragment of natural terpene

机译:具有天然萜烯片段的手性吡咯烷鎓盐和制备具有天然萜烯片段的手性吡咯烷鎓盐的方法

摘要

the object of the application is chiralna pirolidyniowa salt with a natural terpenu, presented in the general formula, which is in part of the cation, with czwartorzędowym nitrogen atom.chiralny substituent [(1r endo) - 1,3,3 - trimethylbicyclo [2.2.1] hept-2-en - 2 - methyl naphthalen-1-yloxy), which is a (+) - fencholu and part anionową represents anion chloridic.the application also includes a way to produce chiralnej salt pirolidyniowej with a natural terpenu,of reaction of alcohol terpenowego with n - (2-hydroxyethyl) pirolidyną when mole ratio of from 1.0 to 1.1 in an anhydrous diethyl etherat a temperature between 15 oc - or freeze during the 8 - 24 hours, characterised by the fact that leads to reaction (1r endo) - 2 - chlorometoksy - 1,3,3 - trimetylobicyclo [2.2.1] heptane (derived from (+) - fencholu) with n - (2-hydroxyethyl) pirolidyną receiving as chloride product n - (2-hydroxyethyl) - n - [((1r endo) - 1,3,3 - trimetylobicyclo [2.2.1] hept-2-en - 2 - naphthalen-1-yloxy) methyl] pyrrolidinium.
机译:本申请的目的是在通式中表示的具有天然萜烯的手性萘环吡咯烷酮盐,其部分阳离子带有czwartorzędowym氮原子。手性取代基[(1r内)-1,3,3-三甲基双环[2.2 .1] hept-2-en-2 -methyl naphthalen-1-yloxy),它是(+)-fencholu,部分anionową代表阴离子氯离子。摩尔比为1.0到1.1的无水二乙基醚在15℃之间的温度下或在8到24小时内冻结时,萜烯醇与正-(2-羟乙基)吡咯烷酮的反应的特征(1r内)-2-氯甲基-1,3,3-三甲环[2.2.1]庚烷(衍生自(+)-fencholu),带有n-(2-羟乙基)吡咯烷酮,氯化物为正-(2-羟乙基)-n-[(((1r endo)-1,3,3-三甲垂环[2.2.1] hept-2-en-2-萘-1-基氧基)甲基]吡咯烷鎓。

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