Composition of recombinant or transgenic factor VII, each molecule of factor VII having two N-glycosylation sites with defined glycan units

摘要

Composition of transgenic factor VII (FVII), each molecule of factor VII of the composition having two N-glycosylation sites, characterized in that: - among all the FVII molecules of the composition, the percentage of Galα1,3Gal glycan units is comprised between 0 and 4%, measuring the percentage of Galα1,3Gal glycan units per lectinatransfer with revelation with 4-chloro-1-naphthol, and - because all factor VII sialic acids involve α2-6 bonds, and - why factor VII of the composition is produced by transgenic rabbits.