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NOVEL CHEMICAL COMPOUND CONTAINING ACTIVE ENANTIOMETER S-(-) KETOROLAC TROMETHAMINE FOR THE TREATMENT OF PAIN
NOVEL CHEMICAL COMPOUND CONTAINING ACTIVE ENANTIOMETER S-(-) KETOROLAC TROMETHAMINE FOR THE TREATMENT OF PAIN
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机译:新型活性成分S-(-)酮咯酸曲美托胺化学化合物治疗疼痛
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摘要
The invention relates to a new chemical compound characterised in that it contains the active enantiomer S-(-) ketorolac tromethamine combined with other pharmaceutically acceptable adjuvants or excipients, said compound being advantageous over other NSAIDs and, in particular, the known active principle ketorolac tromethamine, comprising a unique, pure isomer with a better therapeutic index, retaining its therapeutic activity by improving its physicochemical properties, such as solubility or stability, which translates into a decrease in the dose administered, reducing direct gastrointestinal side effects and the time required for the development of the desired therapeutic action. The invention is suitable for use as a medicament for the treatment of pain of moderate to high intensity and can be administered in any form, in the dose range varying from 0.5 milligrams to 30 milligrams.
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