BIOCHEMICAL MOTIF IN CDR3 OF ANTIBODY SEQUENCES DIAGNOSIS AND PATIENTS WITH RELAPSING-REMITTING MULTIPLE SCLEROSIS

摘要

The present disclosure relates to the identification and application of adaptive immune receptor sequences that indicate an elevated risk of developing an adaptive immune receptor-related disease, such as an autoimmune disease (e.g., multiple sclerosis). The biomarkers and methods can further aid in the prophylaxis and treatment of such diseases.