Disclosed in the present invention are a molecular marker, a kit and an application for use in the early diagnosis and prediction of sepsis as a complication of acute kidney injury. The expression of TCONS_00024536 in the blood of patients suffering from sepsis as a complication of acute kidney injury is high. By means of detecting the expression level of TCONS_00024536 in the blood of a patient, it may be determined whether the patient is suffering from sepsis as a complication of acute kidney injury or the probability of suffering from sepsis as a complication of acute kidney injury.
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