SCREENING METHOD FOR CONTINUOUS CULTURE CONDITIONS AND SCREENING DEVICE FOR CONTINUOUS CULTURE CONDITIONS

摘要

Provided is a method and a device for screening continuous culture conditions, capable of selecting a cell line for continuous culture that hardly proliferates after reaching a steady state and that exhibits a high product generation rate with respect to the cell proliferation rate, and capable of selecting a continuous culture condition suitable for such cell line. This screening method and device are for selecting a suspension-type cell line for continuous culture on the basis of at least one index selected from: an index for the maximum {(product generation rate)/(cell proliferation rate)}; an index for the longest total time-period of a G0 period and a G1 period of the cell cycle; and an index for the minimum pathways in the metabolic flux.