首页> 外国专利> COMPOSITION FOR TREATING FINE DUST-CAUSED SKIN CELL DAMAGE OR FOR INHIBITING ANTIBACTERIAL PEPTIDE, COMPRISING HIBISCUS SYRIACUS EXTRACT

COMPOSITION FOR TREATING FINE DUST-CAUSED SKIN CELL DAMAGE OR FOR INHIBITING ANTIBACTERIAL PEPTIDE, COMPRISING HIBISCUS SYRIACUS EXTRACT

机译:用于治疗细粉尘引起的皮肤细胞损伤或抑制抗菌肽的组合物,该组合物包含斜纹肌糖抽提物

摘要

Disclosed in the present specification is a composition comprising a Hibiscus syriacus extract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of at least one selected from the group consisting of IL-36G (NM_019618), PTGS2(NM_000963), XDH(NM_000379), and S100A7(NM_002963), which are all genes having expression levels affected by fine dust in skin cells, is regulated to a normal level and for inhibiting an antibacterial peptide, wherein the expression of the antibacterial peptide S100A7(NM_002963) is regulated to a normal level. By using the composition for treating fine dust-caused skin damage and the composition for inhibiting an antibacterial peptide, gene expression changed by fine dust can return to a normal level to treat skin cell damage and the increased expression of the antibacterial peptide due to various causes can return to a normal level.
机译:在本说明书中公开了一种组合物,其包含芙蓉提取物作为治疗细粉尘引起的皮肤损伤的有效成分,其中至少一种选自IL-36G(均具有在皮肤细胞中细粉尘影响的表达水平的基因NM_019618),PTGS2(NM_000963),XDH(NM_000379)和S100A7(NM_002963)被调节至正常水平并用于抑制抗菌肽,其中抗菌肽S100A7(NM_002963)的浓度调节到正常水平。通过使用用于治疗细粉尘引起的皮肤损伤的组合物和用于抑制抗菌肽的组合物,由细粉尘改变的基因表达可以恢复到正常水平以治疗皮肤细胞损伤和由于各种原因引起的抗菌肽表达的增加。可以恢复到正常水平。

著录项

  • 公开/公告号WO2019066252A3

    专利类型

  • 公开/公告日2019-05-16

    原文格式PDF

  • 申请/专利权人 AMOREPACIFIC CORPORATION;

    申请/专利号WO2018KR09516

  • 发明设计人 KIM HYOUNG-JUNE;LEE TAE RYONG;

    申请日2018-08-20

  • 分类号A61K8/9789;A61K36/185;A23L33/105;A61Q19;A61Q17;

  • 国家 WO

  • 入库时间 2022-08-21 11:55:23

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