首页> 外国专利> PHARMACEUTICAL COMPOSITION CONTAINING ANTICANCER DRUG-SUPPORTED NANOSTRUCTURE AS ACTIVE INGREDIENT FOR TREATMENT OF LIVER CANCER

PHARMACEUTICAL COMPOSITION CONTAINING ANTICANCER DRUG-SUPPORTED NANOSTRUCTURE AS ACTIVE INGREDIENT FOR TREATMENT OF LIVER CANCER

机译:包含抗癌药支持的纳米结构的药物组合物,作为治疗肝癌的有效成分

摘要

The present invention relates to a pharmaceutical composition containing an anticancer drug-supported nanostructure for treatment of liver cancer and, more specifically, to a pharmaceutical composition for treatment of liver cancer, the pharmaceutical composition containing, as an active ingredient, a nanostructure in which an anticancer drug is supported on a polymer (pPBA) formed from a combination of phenyl boronic acid with a maleic acid anhydride polymer. The nanostructure of the present invention has an excellent tumor proliferation inhibitory effect in cancer, especially, liver cancer, has an excellent drug delivery effect to a tumor site, can function as a tumor indicator by specifically binding to cancer cells, and is stably metabolized in the living body, and thus the nanostructure is expected to be widely used in a medical field.
机译:本发明涉及一种药物组合物,该药物组合物包含用于治疗肝癌的抗癌药物支持的纳米结构,更具体地,涉及一种用于治疗肝癌的药物组合物,该药物组合物包含作为活性成分的纳米结构,其中抗癌药负载在由苯基硼酸与马来酸酐聚合物的组合形成的聚合物(pPBA)上。本发明的纳米结构在癌症特别是肝癌中具有优异的肿瘤增殖抑制作用,对肿瘤部位具有优异的药物递送作用,可以通过与癌细胞特异性结合而起到肿瘤指示剂的作用,并且可以在体内稳定地代谢。因此,纳米结构有望在医学领域得到广泛应用。

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