METHOD FOR PREPARING PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING COGNITIVE DISORDER-ASSOCIATED DISEASES, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING COGNITIVE DISORDER-ASSOCIATED DISEASES, PREPARED BY PREPARATION METHOD

摘要

The present invention relates to a method for preparing a pharmaceutical composition for preventing or treating cognitive disorder-associated diseases, and a pharmaceutical composition for preventing or treating cognitive disorder-related diseases, prepared by the preparation method, the pharmaceutical composition containing microparticles comprising donepezil and a biodegradable polymer, wherein the microparticles are formed such that donepezil is uniformly dispersed in a spherical biodegradable polymer. The present invention can maintain an effect of preventing or treating cognitive disorder-associated diseases for a month with one injection in order to solve the inconvenience of daily drug administration. In addition, since preparation is carried out such that the average diameter of particles is maintained in a predetermined micro-size, a foreign body sensation and pain are reduced during administration to a patient by injection, and thus administration by injection can be facilitated.