Baculovirus System - Methods for Enhancing the Biological Effect of Produced Recombinant Adeno-Associated Viruses

摘要

Methods and compositions useful for the production of recombinant AAV (rAAV) in insect cells are provided herein. In some embodiments, the methods and compositions include the use of modified Kohl sequences to express AAV VP1 protein in an amount useful for producing infectious rAAV particles.