Dipeptidyl peptidase-4 inhibitor for topical ocular treatment of retinal neurodegenerative diseases

摘要

The present invention provides dipeptidyl peptidase-4 inhibitors for use in topical ocular treatment and / or prevention of retinal neurodegenerative diseases, particularly diabetic retinopathy and its associated microvascular disorders, including saxagliptin and cytarglyptin. It is about inhibitors. The present invention also includes pharmaceutical topical ophthalmic compositions for use in topical treatment and / or prevention of the above diseases.