Biomarkers for diagnosing diabetic retinopathy and uses thereof

摘要

The present invention relates to a biomarker for the diagnosis of diabetic retinopathy and a use thereof. Specifically, clinical data and biological samples of a diabetic elderly patient group are collected to identify diabetic retinopathy phenotype, and serum metabolites are profiled using chromatography/mass spectrometry to determine the diabetic retinopathy in diabetic patients when using glutamine, glutamic acid and glutamine/glutamic acid ratio in the metabolites. Therefore, the metabolite marker can be usefully used to determine whether the diabetic retinopathy is present.