Compounds, processes for obtaining the compounds, pharmaceutical compositions, uses of the compounds and methods for treating mental disorders and / or sleep disorders

摘要

The present invention relates to novel and progressive pharmacologically active benzimidazole derivative compounds having surprisingly high affinity for melatonin MT ₁ and MT ₂ receptors and low affinity for CYP450 complex enzyme, particularly CYP1A2. The present invention also relates to novel and advanced synthetic routes of these compounds, to pharmaceutical compositions comprising such compounds and to processes for the manufacture of said compositions, to the use of such receptors in the treatment of psychiatric and / or sleep disorders (especially depression, anxiety , Disorders of the biological cycle). Desc / Clms Page number 2