1 2 A B Human binding molecules capable of neutralizing influenza A viruses of phylogenetic group 1 and phylogenetic group 2 and influenza B viruses

摘要

The present invention relates to a human monoclonal antibody which binds to epitopes in the stem region of hemagglutinin of influenza B virus as well as influenza A viruses of phylogenetic groups 1 and 2 and has a broad neutralizing activity against influenza viruses / RTI The present disclosure provides compositions comprising a binding molecule, a nucleic acid molecule encoding the sequence, and a binding molecule. The binding molecule can be used for the diagnosis, prevention and / or treatment of influenza A virus as well as influenza B viruses of phylogenetic groups 1 and 2.