The present invention, a bellows frame having a concave-convex structure on at least one of the outer surface and the inner surface using a three-dimensional printing technology, and a method of manufacturing the same, and the mucosa portion formed on the inner surface of the bellows frame and the concave-convex structure on the outer surface The present invention relates to an artificial respiratory system substitute including a circular cartilage formed along the circumference of the groove, and a method of manufacturing the same.
展开▼