1 / 3 Peptidyl arginine deiminase 1 and/or 3 activator compounds in the epidermis and used thereof

摘要

The present invention relates to a pharmaceutical composition comprising at least one active agent used alone or in combination in a cosmetic and / or pharmaceutical composition, namely a peptidyl arginine dehydrogenase from the epidermis by caffeine, acefylline and / or theobromine, Lt; RTI ID = 0.0 (PAD) / RTI The present invention also relates to cosmetic and / or therapeutic agents, alone or in combination, for improving barrier functions of the epidermis, preventing and / or treating symptoms associated with dry skin, and / or improving and / To the use of agents having the above-mentioned activity. Finally, the present invention relates to increasing the activity of PADl and / or PAD3 in the epidermis.