首页> 外国专利> SOX18 A biomarker for diagnosing asthma or chronic obstructive pulmonary disease comprising SOX18 and the uses thereof

SOX18 A biomarker for diagnosing asthma or chronic obstructive pulmonary disease comprising SOX18 and the uses thereof

机译:SOX18用于诊断哮喘或慢性阻塞性肺疾病的生物标志物,其包含SOX18及其用途

摘要

The present invention relates to a composition for diagnosing asthma or chronic obstructive pulmonary disease, which comprises an agent for measuring the level of mRNA of a protein of SOX18 or a gene thereof, and a kit for the diagnosis of asthma or chronic obstructive pulmonary disease, A method for providing information for diagnosing obstructive pulmonary disease, and a method for screening for a therapeutic agent for asthma or chronic obstructive pulmonary disease. The present invention provides a composition for the diagnosis of asthma or chronic obstructive pulmonary disease so that the expression level of the protein or its gene whose expression changes in asthma or chronic obstructive pulmonary disease patients can be measured and compared to determine the early diagnosis of asthma or chronic obstructive pulmonary disease And disease severity can be significantly predicted or understood. In addition, the composition for diagnosing asthma or chronic obstructive pulmonary disease of the present invention is a simple and effective method for early diagnosis of asthma or chronic obstructive pulmonary disease by enabling non-invasive diagnosis, such as blood or urine test.
机译:本发明涉及用于诊断哮喘或慢性阻塞性肺疾病的组合物,其包含用于测量SOX18蛋白或其基因的mRNA水平的试剂,以及用于诊断哮喘或慢性阻塞性肺疾病的试剂盒,提供用于诊断阻塞性肺疾病的信息的方法,以及用于筛选哮喘或慢性阻塞性肺疾病的治疗剂的方法。本发明提供了一种用于诊断哮喘或慢性阻塞性肺疾病的组合物,从而可以测量和比较在哮喘或慢性阻塞性肺疾病患者中其表达变化的蛋白质或其基因的表达水平,以确定哮喘的早期诊断。或慢性阻塞性肺疾病可以严重预测或了解疾病的严重程度。另外,本发明的用于诊断哮喘或慢性阻塞性肺疾病的组合物是通过能够进行非侵入性诊断(例如血液或尿液检查)来早期诊断哮喘或慢性阻塞性肺疾病的简单有效的方法。

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