FIELD: biotechnology.SUBSTANCE: cell line of rat glioma C6-DDA is resistant to cytotoxic action of N-acyl dopamine as a test culture for studying mechanisms of action of bioactive lipids, is obtained on the basis of the rat C6 glioma line and is characterized by immunity to the cytotoxic effect of dopamine amides of natural polyunsaturated fatty acids to concentration of 40 mcM, presence of long or multiple short processes and increased expression of markers of astrocytic differentiation of GFAP, SOX2, hydrolases of FAAH fatty acid amides, noradrenaline transporter NET and oxidoreductase ecto-NOX, is deposited in the Russian National Collection of Industrial Microorganisms, registration number N-173.EFFECT: invention relates to a rat C6-DDA glioma cell line.1 cl, 2 tbl, 2 ex
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机译：领域：生物技术。物质：大鼠神经胶质瘤C6-DDA细胞系具有抗N-酰基多巴胺的细胞毒性作用，作为研究生物活性脂质作用机制的试验培养物，是在大鼠C6神经胶质瘤系的基础上获得的，其特点是对天然多不饱和脂肪酸多巴胺酰胺的浓度达40 mcM的细胞毒性具有免疫力，存在长或多个短过程，并且GFAP，SOX2，FAAH脂肪酸酰胺水解酶，去甲肾上腺素转运蛋白的星形细胞分化标记物的表达增加NET和氧化还原酶ecto-NOX保藏在俄罗斯国家工业微生物集合中，注册号N-173。效果：本发明涉及大鼠C6-DDA神经胶质瘤细胞系。1cl，2 tbl，2 ex
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