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WATER-SOLUBLE DERIVATIVE OF CHLOROPHYLL α MODIFIED BY MYRISTIC ACID FRAGMENT

机译：肉豆蔻酸片段修饰的叶绿素α的水溶性衍生物

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摘要

FIELD: chemistry.;SUBSTANCE: invention relates to a water-soluble derivative of chlorophyll a modified by a fragment of myristic acid. ; .;EFFECT: new biologically active compound of the chlorin series has been obtained, which has an antibacterial effect, which can be used as a potential photosensitizer (PS) for antibacterial PDT.;1 cl, 4 dwg, 3 ex

机译：发明领域本发明涉及一种由肉豆蔻酸的片段修饰的叶绿素 a 的水溶性衍生物。 ; 。;效果：已获得新的二氢卟酚系列生物活性化合物，该化合物具有抗菌作用，可用作抗菌PDT的潜在光敏剂（PS）。; 1 cl，4 dwg，3 ex 展开▼

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公开/公告号RU2680523C1

专利类型

公开/公告日2019-02-22

原文格式PDF

申请/专利权人 FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO OBRAZOVANIYA IVANOVSKIJ GOSUDARSTVENNYJ KHIMIKO-TEKHNOLOGICHESKIJ UNIVERSITET (IGKHTU);
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申请/专利号RU20170141961

发明设计人 KHUDYAEVA IRINA STEPANOVNA (RU);KUSTOV ANDREJ VLADIMIROVICH (RU);BEREZIN DMITRIJ BORISOVICH (RU);KUDAYAROVA TATYANA VLADIMIROVNA (RU);BELYKH DMITRIJ VLADIMIROVICH (RU);
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申请日2017-12-01

分类号C07D487/22;A61K31/409;

国家 RU

入库时间 2022-08-21 11:46:21

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1. 水溶性阴离子型细菌叶绿素衍生物及其用途 [P] . 中国专利： CN102002048B . 2012.11.28

2. 水溶性阴离子型细菌叶绿素衍生物及其用途 [P] . 中国专利： CN102002048A . 2011-04-06

3. CHLOROPHYLL DERIVATIVES α, MODIFIED BY MYRISTIC ACID FRAGMENTS [P] . 俄罗斯专利： RU2673888C1 . 2018-12-03

机译：肉豆蔻酸片段修饰的叶绿素衍生物α

4. Isolated nucleic acid fragments encoding an enzyme modifier of vegetable fatty acids associated with the formation of conjugated double joints, fusion genes.Host cells transformed, seeds, oils, methods of modification of the degree of fatty acids with conjugated double unions in a host cell.Methods of producing seed oil containing fatty acids with conjugated double unions in seed plants.Methods for the production of fatty acid modifying enzymes associated with formation of conjugated double joints,Methods of isolation of fragments of nucleic acids and their subfragmentos functionally equivalent encoding an enzyme modifier of vegetable fatty acids associated with the formation of uniS conjugated double, animal feed, methods of improving the quality of the carcass of an animal and complement [P] . BR9913382A . 2001-09-25

机译：编码植物脂肪酸的酶修饰物的分离的核酸片段，与共轭双接头，融合基因的形成有关。转化的宿主细胞，种子，油，在宿主细胞中用共轭双接头修饰脂肪酸程度的方法。在种子植物中生产具有共轭双键脂肪酸的种子油的方法。与共轭双键的形成相关的脂肪酸修饰酶的生产方法;核酸片段的分离方法及其功能等同的编码酶修饰剂的亚片段脂肪酸与uniS共轭双链的形成有关的信息，动物饲料，改善动物car体和补体质量的方法

5. Nucleic acid fragment isolated, complement, chimeric gene, host cell transformed plant or plant transformed host cell, plant or seed.The oil method of amendment of the level of fatty acids in a plant or host cell, method of production of oil seeds containing fatty acids.Method for the production of modifying enzymes of fatty acids, method for isolating the fragments of nucleic acids and their subfragmentos functionally equivalent.Animal food and method for improving the quality of an animal carcass [P] . BR0013309A . 2002-05-28

机译：分离的核酸片段，补体，嵌合基因，宿主细胞转化的植物或植物转化的宿主细胞，植物或种子。改变植物或宿主细胞中脂肪酸水平的上油方法，生产含脂肪的油种子的方法脂肪酸。脂肪酸修饰酶的生产方法，核酸片段及其功能相同的亚片段的分离方法。动物食品和提高动物car体质量的方法

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2. Science Letters: A modified chlorophyll absorption continuum index for chlorophyll estimation [J] . YANG Xiao-hua, HUANG Jing-feng, WANG Fu-min, 浙江大学学报（英文版）（A辑：应用物理和工程） . 2006,第012期

3. Myristic Acid （MA） Promotes Adipogenic Gene Expression and the Differentiation of Porcine Intramuscular Adipocyte Precursor Cells [J] . LU Nai-sheng, SHU Gang, XIE Qiu-ping, 农业科学学报：英文版 . 2014,第011期

4. Recombinant water-soluble chlorophyll protein from Brassica oleracea Var. botrys binds various chlorophyll derivatives [J] . Schmidt K., Fufezan C., Krieger-Liszkay A., Biochemistry . 2003,第24期

5. Nucleic acid probe and stain based on water-soluble tetraphenylethene derivatives modified with different kinds of amino binding groups: The role of hydrogen bond [J] . Li Xu, Danqing Wei, Zece Zhu, Sensors and Actuators . 2016,第octa期

6. Synthesis and characterization of folic acid modified water-soluble chitosan derivatives for folate-receptor-mediated targeting [J] . JingH., GuoZ., GuoW., Bioorganic and Medicinal Chemistry Letters . 2012,第10期

7. CHROMATOGRAPHIC AND ELECTROPHORETIC PROFILES OF TWO ACIDIC WATER-SOLUBLE FULLERENE DERIVATIVES [C] . Najla Gharbi, Michael Brettreich, Colin Crowley, International Symposium on Fullerenes, Nanotubes, and Carbon Nanoclusters, May 12-17, 2002, Philadelphia . 2002

8. Synthesis and study of arylboronic acid derivatives for covalent recognition and transport of neutral water-soluble compounds [D] . Mohler, Linda Kay 1993

9. Antioxidant capacity and hepatoprotective activity of myristic acid acylated derivative of phloridzin [O] . Chunli Liu, Chunlong Yuan, Hosahalli S. Ramaswamy, 2019

10. Increasing amounts of dietary myristic acid modify the plasma cholesterol level and hepatic mass of Scavenger receptor BI without affecting bile acid biosynthesis in hamsters [O] . Loison, Carole, Mendy, François, Serougne, Colette, 2002

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