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SYSTEM, APPARATUS, AND METHOD FOR SEQUENCE-BASED ENZYME EC NUMBER PREDICTION BY DEEP LEARNING

机译:通过深度学习预测基于序列的酶EC数的系统,装置和方法

摘要

An apparatus, computer program product, and method are provided for the determination of one or more components of an EC number through the application of a level-by-level modeling approach capable of conducting feature reconstruction and classifier training simultaneously, based on encoded aspects of a sequence listing for a protein with an unknown function. The method includes receiving a sequence source data object associated with an enzyme; extracting a sequence data set from the sequence source data object; encoding the sequence data set into a first and second encoded sequence; generating a first predicted characteristic of the enzyme by applying the first and second encoded sequence to a first level of a model comprising a plurality of levels; and generating a second predicted characteristic of the enzyme by applying the first and the second encoded sequences to a second level of the model comprising a plurality of levels.
机译:提供了一种设备,计算机程序产品和方法,用于通过应用能够基于特征码的编码方面同时进行特征重构和分类器训练的逐级建模方法来确定EC号的一个或多个组件。功能未知的蛋白质的序列表。该方法包括接收与酶相关的序列源数据对象;从序列源数据对象中提取序列数据集;将序列数据集编码为第一和第二编码序列;通过将第一和第二编码序列应用于包括多个水平的模型的第一水平,产生酶的第一预测特征;通过将第一和第二编码序列应用于包括多个水平的模型的第二水平,产生酶的第二预测特征。

著录项

  • 公开/公告号EP3698365A1

    专利类型

  • 公开/公告日2020-08-26

    原文格式PDF

  • 申请/专利号EP20180855200

  • 发明设计人 GAO XIN;LI YU;

    申请日2018-10-16

  • 分类号G16B15/20;G16B40/30;

  • 国家 EP

  • 入库时间 2022-08-21 11:40:04

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