NEW USE OF CELL-PERMEABLE PEPTIDE INHIBITORS OF JNK SIGNAL TRANSDUCTION PATHWAY FOR TREATMENT OF VARIOUS DISEASES

摘要

To provide the use of protein kinase inhibitors for treatment of diseases related strongly to JNK signaling.SOLUTION: The present invention provides the use of a chimeric peptide including covalently linked at least one first domain and at least one second domain, for preparation of a pharmaceutical composition for treating cystitis. The first domain comprises a trafficking sequence, and the second domain comprises a JNK inhibitor sequence comprising less than 150 amino acids in length. The chimeric peptide includes all D amino sequences described in SEQ ID NO: 11.SELECTED DRAWING: None