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Affinity chromatography carrier, chromatography column, purification method, and target substance purified by the method

机译:亲和色谱载体,色谱柱,纯化方法以及通过该方法纯化的目标物质

摘要

PROBLEM TO BE SOLVED: To provide a carrier for affinity chromatography having a high flow rate characteristic and target material capture characteristic although a protein ligand is used.SOLUTION: A carrier for affinity chromatography is modified by a hydrophilic polymer and linker compound. In this carrier, a protein ligand is further fixed through an active group on the linker compound fixed on a support body, and the linker length between the ligand and the support body is 30 or more in atomic number.SELECTED DRAWING: None
机译:解决的问题:提供亲和色谱的载体,尽管使用蛋白质配体,但具有高流速特性和目标物质的捕获特性。解决方案:亲和色谱的载体被亲水性聚合物和连接剂化合物改性。在该载体中,蛋白质配体通过固定在支持体上的连接基化合物上的活性基团进一步固定,并且配体与支持体之间的连接基长度为原子序数30以上。

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