C5 ANTIBODIES AND METHODS FOR PREVENTING AND TREATING COMPLEMENT-RELATED DISEASES

摘要

To provide a composition containing a complement inhibitor, a method for treating or preventing complement-related disorder, and a use therefor.SOLUTION: The present invention provides a monoclonal antibody or an antigen-binding fragment thereof that specifically binds to a human complement component 5 (C5) protein, comprising heavy chain CDR1, heavy chain CDR2, heavy chain CDR3, light chain CDR1, light chain CDR2, and light chain CDR3 selected from specific sequences, and a pharmaceutical composition comprising the same, and a diagnostic kit for complement-related disease.SELECTED DRAWING: None