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Rationally designed synthetic antibody libraries and their use
Rationally designed synthetic antibody libraries and their use
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机译:合理设计的合成抗体文库及其用途
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摘要
The present disclosure provides methods for generating libraries of antibody-encoding polynucleotides by specifically designing the libraries with directed sequence and length diversity. The libraries are designed to reflect the preimmune repertoire naturally created by the human immune system and are based on rational design informed by examination of publicly available databases of human antibody sequences.
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