Method for treating multiple osteochondroma (MO)

摘要

The present invention inhibits the formation of osteochondroma in a subject with multiple osteochondroma (MO) by administering to the subject parobarotene (also known as R667) or a pharmaceutically acceptable salt thereof, It features a method of reducing its size and delaying its growth. The methods described herein can also ameliorate complications associated with osteochondroma formation and growth in subjects with MO. A method for inhibiting the formation of osteochondroma in a subject with multiple osteochondroma (MO), comprising: palobaroten ((E) -4- (2- {3-[(1H-pyrazol-1-yl) methyl) ] -5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl} vinyl) benzoic acid) or a pharmaceutically acceptable salt thereof in the formation of the osteochondroma Administering to said subject in an amount effective to inhibit. [Selection] Figure 1