Chiral synthesis of N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-1,2,4triazolo4,3-Apyrazines

摘要

Disclosed is a novel chiral synthesis of N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines of Formula (I):; or a solvate thereof. The novel chiral synthesis avoids the use of protection/deprotection steps.