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COMBINATION OF STRUCTURAL VARIATIONS AND SINGLE NUCLEOTIDE CHANGES IN ONE STATISTICAL MODEL FOR IMPROVED ANTIMICROBIAL DRUG THERAPY SELECTION
COMBINATION OF STRUCTURAL VARIATIONS AND SINGLE NUCLEOTIDE CHANGES IN ONE STATISTICAL MODEL FOR IMPROVED ANTIMICROBIAL DRUG THERAPY SELECTION
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机译:一种改进的抗微生物药物治疗选择的统计模型中的结构变化和单核苷酸变化的组合
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摘要
The invention relates to a method of determining an antimicrobial drug resistance profile for a microorganism, wherein nucleic acid sequences of the microorganism are analyzed for structural variations of the genome comprising at least a change in the genome comprising more than one base, as well as for single nucleotide polymorphisms (SNPs), as well as a method of determining an infection of a patient with a microorganism potentially resistant to antimicrobial drug treatment and a method of selecting a treatment of a patient suffering from an infection with a potentially resistant microorganism, wherein the data of the antimicrobial drug resistance profile are applied.
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