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COMPOSITIONS AND METHODS FOR TREATING OR AMELIORATING FIBROSIS, SYSTEMIC SCLEROSIS, SCLERODERMA AND GRAFT VERSUS HOST DISEASE
COMPOSITIONS AND METHODS FOR TREATING OR AMELIORATING FIBROSIS, SYSTEMIC SCLEROSIS, SCLERODERMA AND GRAFT VERSUS HOST DISEASE
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机译:用于治疗或改善纤维化,系统性硬化症,菌皮和移植物抗宿主病的组合物和方法
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摘要
Provided are Adenosine Deaminase (ADA), or a polypeptides or peptides having an ADA activity, or an ADA conjugate, pharmaceutical compositions and formulations, products of manufacture and kits, and methods containing them for the prevention and treatment of a scleroderma-associated vasculopathy, in particular proliferative obliterative vasculopathy, progressive obliterative vasculopathy or an idiopathic obliterative vasculopathy and/or preventing or decreasing the progression of scleroderma, wherein optionally the scleroderma comprises a local scleroderma or a diffuse, or a systemic scleroderma.
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