首页> 外国专利> compound, method for treating and / or preventing a disease distinguished by deficient signaling of neurotropins and / or other trophic factors, use of a compound, pharmaceutical composition, combination product, kit of parts, and processes for preparing a compound and a pharmaceutical composition.

compound, method for treating and / or preventing a disease distinguished by deficient signaling of neurotropins and / or other trophic factors, use of a compound, pharmaceutical composition, combination product, kit of parts, and processes for preparing a compound and a pharmaceutical composition.

机译:化合物,用于治疗和/或预防以神经营养蛋白和/或其他营养因子信号不足为特征的疾病的方法,化合物的用途,药物组合物,组合产品,试剂盒以及制备化合物和药物组合物的方法。

摘要

The present invention relates to a new use of 4-phenoxy-phenyl-1,3,5-triazine derivatives or pharmaceutically acceptable salts thereof according to formula i, wherein r1, r2 and i have meanings as given in description, as medicines for the treatment and / or prevention of diseases characterized by decreased signaling of neurotrophins and / or other trophic factors. In particular, the invention relates to the treatment of such diseases in patients with the val66met mutation in the brain derived neurotrophic factor gene.
机译:本发明涉及式I的4-苯氧基-苯基-1,3,5-三嗪衍生物或其药学上可接受的盐的新用途,其中r1,r2和i具有说明书中给出的含义,作为该药物的用途治疗和/或预防以神经营养蛋白和/或其他营养因子信号转导为特征的疾病。特别地,本发明涉及在患有脑源性神经营养因子基因中的val66met突变的患者中治疗此类疾病。

著录项

  • 公开/公告号BR112019012709A2

    专利类型

  • 公开/公告日2019-11-26

    原文格式PDF

  • 申请/专利权人 ALZECURE PHARMA AB;

    申请/专利号BR20191112709

  • 申请日2017-12-21

  • 分类号A61K31/53;A61P25/28;C07D251/30;

  • 国家 BR

  • 入库时间 2022-08-21 11:18:31

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