CRYSTALLINE FORM OF {5- (4-BROMO-PHENYL) -6- 2- (5-BROMO-PYRIMIDIN-2-ILOXI) -ETOXI -PYRIMIDIN-4-IL} -SULPHAMIDE, PHARMACEUTICAL COMPOSITION, USE OF A FORM CRYSTALLINE COMPOUND {5- (4-BROMO-PHENYL) -6- 2- (5-BROMO-PYRIMIDIN-2-ILOXI) -ETOXI -PYRIMIDIN-4-IL} -SULPHAMIDE, AND, TREATMENT METHOD

摘要

the present invention relates to new crystalline forms of {5- (4-bromo-phenyl) -6- [2- (5-bromo-pyrimidine-2-yloxy) -ethoxy] -pyrimidine-4-yl} -sulfamide , processes for preparing the same, pharmaceutical compositions comprising said crystalline forms, pharmaceutical compositions prepared from such crystalline forms, and their use as endothelin receptor antagonists. it also refers to new uses of {5- (4-bromo-phenyl) -6- [2- (5-bromo-pyrimidine-2-yloxy) -ethoxy] -pyrimidine-4-yl} -sulfamide, alone or in combination with other active ingredients or therapeutic agents.