copolymers in amphiphilic blocks, micelles and methods for treating or preventing heart failure

摘要

micelle-forming amphiphilic block copolymers for use in targeting cardiac cells (eg fibrotic cells) of an individual suffering from heart failure, micelles that contain the micelle-forming amphiphilic block copolymers together with a cardioactive agent and compositions and methods related to treating or preventing heart failure, for example, heart failure with preserved ejection fraction (hfpef), also known as diastolic heart failure.