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IMPROVING THE STABILITY AND PURITY AND INCREASING THE BIOTAILABILITY OF HUMAN MILK OILOSACCHARIDES OR SUCH STAGES OR MIXTURES THEREOF
IMPROVING THE STABILITY AND PURITY AND INCREASING THE BIOTAILABILITY OF HUMAN MILK OILOSACCHARIDES OR SUCH STAGES OR MIXTURES THEREOF
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机译:改善人乳油糖或此类中间体或混合物的稳定性和纯度,并提高其生物活性
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摘要
The present application describes methods for spray drying human milk oligosaccharide (HMO) or HMO precursor or a mixture of HMOs from which substantially all of the water has been removed; and from which substantially all of the residue of an organic solvent, in particular toluene or a substituted toluene and / or a lower alkanol, is thereby removed; and that the glass transition temperature of the HMOs is increased; and, furthermore, its / its stability for prolonged storage at temperatures above 25 ° C is improved; and / or its / its mammalian bioavailability is thereby further increased.
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