首页> 外国专利> IMPROVING THE STABILITY AND PURITY AND INCREASING THE BIOTAILABILITY OF HUMAN MILK OILOSACCHARIDES OR SUCH STAGES OR MIXTURES THEREOF

IMPROVING THE STABILITY AND PURITY AND INCREASING THE BIOTAILABILITY OF HUMAN MILK OILOSACCHARIDES OR SUCH STAGES OR MIXTURES THEREOF

机译:改善人乳油糖或此类中间体或混合物的稳定性和纯度,并提高其生物活性

摘要

The present application describes methods for spray drying human milk oligosaccharide (HMO) or HMO precursor or a mixture of HMOs from which substantially all of the water has been removed; and from which substantially all of the residue of an organic solvent, in particular toluene or a substituted toluene and / or a lower alkanol, is thereby removed; and that the glass transition temperature of the HMOs is increased; and, furthermore, its / its stability for prolonged storage at temperatures above 25 ° C is improved; and / or its / its mammalian bioavailability is thereby further increased.
机译:本申请描述了喷雾干燥人乳寡糖(HMO)或HMO前体或基本上已除去所有水的HMO混合物的方法。从中基本上除去有机溶剂,特别是甲苯或取代的甲苯和/或低级链烷醇的所有残余物; HMO的玻璃化转变温度升高;并且,其在25℃以上的温度下长时间储存​​的稳定性得到改善;和/或其哺乳动物的生物利用度因此被进一步提高。

著录项

  • 公开/公告号DK201900098U1

    专利类型

  • 公开/公告日2020-01-16

    原文格式PDF

  • 申请/专利权人 GLYCOM A/S;

    申请/专利号DK2019BA00098U

  • 申请日2019-12-02

  • 分类号C07H1/06;A23L33;A61K31/702;C07H3/06;

  • 国家 DK

  • 入库时间 2022-08-21 11:17:56

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