Trans-4-{ 2-4-(2,3-dichlorophenyl)-piperazin-1-yl-ethyl} -n,n-dimethylcarbamoyl-cyclohexylamine for treating negative symptoms of schizophrenia

摘要

The present invention relates to trans-4-{ 2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]- ethyl} -N,N-dimethylcarbamoyl-cyclohexylamine (cariprazine) and pharmaceutically acceptable salts and hydrates and solvates and polymorphs thereof for use in the treatment of primary negative symptoms of schizophrenia and/or predominantly negative symptoms of schizophrenia.