Amidosulfate derivatives of 4-(1-phenyl-1H-1,2,3triazol-4-yl)-phenol, 4-(1-phenyl-1H-1,2,3triazol-4-yl)-phenol derivatives, their medical use and the preparation method of 4-(1-phenyl-1H-1,2,3triazol-4-yl)-phenol sulfate derivatives

摘要

The scope of the notification is 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol amidosarbonates and 4-(1-phenyl-1H-[1241,2,3]triazol-4-yl)-phenol derivatives as new compounds. The first medical use of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol derivs., and the first medical use of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol, is also covered by the notification. The scope of the notification is also the application of new relationshipsas a substance with the characteristics of a steroid sulphate inhibitor and/or an oestrogen receptor modulator. The notification shall also include the use of new compounds as an antimicrobial agent and/or an oestrogen receptor modulator. In particular, 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol derivatives are medically used as medicines for cancer therapy. The notification shall also cover the way in which those new relationships are obtained.where the 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol derivatives are an intermediate product from which starch derivatives are directly obtained.