USE OF SEMAPHORIN-4D INHIBITORY MOLECULES IN COMBINATION WITH AN IMMUNE MODULATING THERAPY TO INHIBIT TUMOR GROWTH AND METASTASES

摘要

Provided herein are methods for inhibiting, delaying, or reducing tumor growth and metastases of plexin-Bl-expressing cancer cells in a subject, comprising administering to the subject an effective amount of an isolated binding molecule which specifically binds to semaphorin-4D (SEMA4D) in combination with an effective amount of at least one other immune modulating therapy.