The present invention relates to the technical field of marine antifouling materials. Disclosed is a main-chain degradable copper polyacrylate resin, a preparation method therefor and an application thereof. The main-chain degradable copper polyacrylate resin is prepared from the following components in parts by weight: 100 parts by weight of an acrylate prepolymer, 5-50 parts by weight of a copper-containing compound, 0-75 parts by weight of monocarboxylic acid, and 5-150 parts by weight of an organic solvent. The acrylate prepolymer is mainly prepared from the following components: a solvent, a cyclic monomer, a vinyl monomer, (methyl)propenoic acid, and an initiator. According to the resin of the present invention, the copper ester bonds at the side chain and polyester chain segments at the main chain can be hydrolyzed under seawater attach, the dependence of a conventional self-polishing material on the navigational speed is avoided, the coating surface is self-updated in static seawater due to a hydrolytic degradation effect, an antifouling agent can be effectively controlled to be released at a constant speed, and the anti-fouling requirements of ships at a low navigational speed, offshore production platforms and other facilities are met; moreover, the resin has good drag reduction performance.
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